Caudate Nucleus Is Critically Involved in Trace Eyeblink Conditioning
نویسندگان
چکیده
منابع مشابه
Caudate nucleus is critically involved in trace eyeblink conditioning.
The basal ganglia are a collection of brain regions involved with motor planning and initiation. The major site of cortical and thalamic input into the basal ganglia network is the striatum, which includes a differentiated caudate nucleus (CN) and the putamen in rabbits. Trace eyeblink conditioning (EBC) is a forebrain-dependent associative learning task in which a stimulus-free time interval s...
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Trace eyeblink conditioning (EBC) is an associative learning task in which a stimulus-free trace period separates the presentation of a behaviorally neutral conditioned stimulus (CS; whisker stimulation) from a behaviorally salient unconditioned stimulus (US; air puff to the eye). Repeated pairings of the CS with the US results in the emergence of the conditioned response (CR; eyeblink after CS...
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Synaptic plasticity plays a role during trace eyeblink conditioning (TEBC). Synaptophysin (Syn) is a major integral transmembrane protein, located particularly in the synaptic vesicles, and is considered a molecular marker of synapses. In addition, Syn immunoreactivity is an important indicator of synaptic plasticity. In this study, we used immunohistochemical techniques to assess changes in Sy...
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which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Trace eyeblink conditioning in mice is dependent upon the dorsal medial prefrontal cortex, cerebellum and amygdala: Behavioral characterization and functional circuitry. Alerts: Sign up at eneuro.org/alerts to receive customized email alerts when the fully formatte...
متن کاملEyeblink classical conditioning in H.M.: delay and trace paradigms.
H.M., a well-known subject with bilateral removal of medial-temporal-lobe structures and profound amnesia, performed eyeblink classical conditioning (EBCC) for 21 90-trial sessions in the 400-ms delay and 900-ms trace paradigms. A 2nd amnesic subject with temporal lobe lesions and 2 normal control subjects (NCSs) were also conditioned. Acquisition occurred in both paradigms for all subjects. Ac...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2009
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.3119-09.2009